The permutation role of fenugreek seeds starch and Gunda glue as a binder in Paracetamol tablets
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ABSTRACT:
Trigonella-foenum graecum (fenugreek) has been reported to contain upto 56.0% starch. The starch was extracted
from the seeds of Trigonella-foenum graecum (fenugreek). The entire seeds were subjected to size reduction, followed by successive extractions with chlorinated hydrocarbons to separate the husk from the 'core and oily portion' to yield about 40%w/w of the husk. The dried husk was further powdered to 180 - 250 µ. The tablets prepared by using powdered husk were evaluated for hardness, friability, weight uniformity, disintegration and dissolution profiles. Cordia gharaf, the fruit is a green berry or ovoid drupe 1 cm in diameter, seated in a saucer-like enlarged calyx. It turns black on ripening and the pulp gets viscid. The sticky pulp is used to make glue. Acetaminophen tablets containing gelatin as a standard binder were formulated and assessed comparatively. Result obtained indicate that fenugreek starch performed as good as gelatin as binder to acetaminophen tablets.
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